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AI for Evidence-Based Medicine

AI for Evidence Generation

How can AI help produce the evidence at each tier of the pyramid?

AI for Evidence Utilization

How can AI fully utilize existing evidence?

AI for Evidence Generation and Utilization

How can AI generate — and make use of — medical evidence?

Systematic Reviews
TrialMind
Agentic systematic literature review
TrialMind
npj Digit Med, 2025
LEADS
Human-AI collaborative review
LEADS
Nat Commun, 2025
Clinical Trials
TrialGPT
Zero-shot trial matching
TrialGPT
Nat Commun, 2024
TrialGPT 2.0
Clinical validation and deployment
TrialGPT 2.0
arXiv, 2026
Case Reports
PMC-Patients
Patient-level case corpus
PMC-Patients
Scientific Data, 2023
Retrieve
LADER
Log-augmented dense retrieval
LADER
SIGIR, 2023
PubMed and Beyond
Survey of AI search tools
PubMed and Beyond
eBioMedicine, 2024
MedCPT
Zero-shot PubMed retriever
MedCPT
Bioinformatics, 2023
PubTator 3.0
Entity-annotated PubMed
PubTator 3.0
Nucleic Acids Res, 2024
Summarize
MedRAG
Benchmarking medical RAG
MedRAG
ACL Findings, 2024
i-MedRAG
Iterative follow-up RAG
i-MedRAG
PSB, 2025
MedReview
Summarizing systematic reviews
MedReview
npj Digit Med, 2025
RAG-Gym
Process‑supervised agentic RAG
RAG-Gym
Nat Commun, 2026
Verify
MedCite
Verifiable answer citations
MedCite
ACL Findings, 2025
Med-V1
Scalable evidence attribution
Med-V1
arXiv, 2026
Agentic orchestration
GeneAgent
Self-verifying gene-set analysis
GeneAgent
Nat Methods, 2025
AgentMD
Tool-augmented risk prediction
AgentMD
Nat Commun, 2025
Medical AI Evaluation

How do we know when medical AI is good enough to trust?

routinely measured
rarely measured